As the GDF11 paper states, you need to take these daily measurements, and place them into a trending spreadsheet. We look at the trending of your HRV, BP, pulse, reaction time to determine your optimal GDF11 dose.
Here are the daily biomarkers that we require:
We give you this Emfit sleep monitor which is an incredible piece of biomarker equipment that goes under your mattress. The Emfit measures everything from HRV, to pulse, percent deep sleep to breathing rate.
What we love most about the Emfit is that it is very, very accurate since it samples biomarkers like HRV every five minutes, which means 96 data points in an average night's sleep. And all you have to do is crawl into bed!
On GDF11, you should see your HRV improve much more dramatically between bedtime and waking. And you should also see your deep sleep percentage go up.
We give you an Omron blood pressure/pulse meter for daily input of these key biomarkers.
BP and pulse should go down on GDF11.
To measure lung function, we give you this Microlife spirometer to measure
peak expiry flow (PEF) and forced expiry in one second (FEV1).
Everyone's PEF improves on GDF11.
Reaction time, a key biomarker of neurological health, is taken daily on HumanBenchmark.com.
ALL members of the GDF11 cohort have seen significant reductions in reaction time.
The Szynalski Online Tone Generator is a simple hearing test you can take on your PC. You just move the slider to the right until you can't hear the tone anymore. This is the highest frequency you can hear which unfortunately goes down with age. You then enter the highest frequency you can hear into your biomarker/trending spreadsheet.
After you start taking GDF11, the highest frequency you can hear will go up quite dramatically and your spreadsheet can graph this for you. This will translate into much better hearing that you will almost certainly notice.
Smell and vision improve significantly on GDF11 also, but we chose hearing as a sensory biomarker since it is the easiest to measure.
Mechanism of action of GDF11 in the senses believed to be moving progenitor cells into an active state in the auditory, retinal and olfactory epithelia.
Hand grip strength is a fun biomarker and let's hear it for a strong handshake! You'll be happy to know that everyone's hand grip improves on GDF11 - typically 15+ percent.
We give you this digital hand grip dynamometer so you can track your hand strength improvement on GDF11.
GDF11 reactivates muscle stem cells (satellite cells), so most of the cohort sees increased lean muscle mass and some body fat reduction. We give you this scale helps us track your body composition progress on GDF11.
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