As the GDF11 paper states, you need to take these daily measurements, and place them into a trending spreadsheet. We look at the trending of your HRV, BP, pulse, reaction time to determine your optimal GDF11 dose.
Here are the daily biomarkers that we require:
We give you this Emfit sleep monitor which is an incredible piece of biomarker equipment that goes under your mattress. The Emfit measures everything from HRV, to pulse, percent deep sleep to breathing rate.
What we love most about the Emfit is that it is very, very accurate since it samples biomarkers like HRV every five minutes, which means 96 data points in an average night's sleep. And all you have to do is crawl into bed!
On GDF11, you should see your HRV improve much more dramatically between bedtime and waking. And you should also see your deep sleep percentage go up.
We give you an Omron blood pressure/pulse meter for daily input of these key biomarkers.
BP and pulse should go down on GDF11.
To measure lung function, we give you this Microlife spirometer to measure
peak expiry flow (PEF) and forced expiry in one second (FEV1).
Everyone's PEF improves on GDF11.
Reaction time, a key biomarker of neurological health, is taken daily on HumanBenchmark.com.
ALL members of the GDF11 cohort have seen significant reductions in reaction time.
We give you this AccuCheck Aviva blood glucose meter to check your waking blood sugar every morning.
Waking glucose should go down with GDF11 supplementation.
The Mimi hearing test is a very accurate hearing test you can take on your phone. We require at least one test per week. Everyone's hearing improves on GDF11, especially in the high frequency range.
Smell and vision improve significantly on GDF11 also, but we chose hearing as a sensory biomarker since it is the easiest to measure.
Mechanism of action of GDF11 in the senses believed to be moving progenitor cells into an active state in the auditory, retinal and olfactory epithelia.
Hand grip strength is a fun biomarker and let's hear it for a strong handshake! You'll be happy to know that everyone's hand grip improves on GDF11 - typically 15+ percent.
We give you this digital hand grip dynamometer so you can track your hand strength improvement on GDF11.
GDF11 reactivates muscle stem cells (satellite cells), so most of the cohort sees increased lean muscle mass and some body fat reduction. We give you this scale helps us track your body composition progress on GDF11.
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