These dogs are hemangiosarcoma free after many years!
Dexter
Hemangiosarcoma (HSA) is a rapidly growing, highly invasive cancer arising from the lining of blood vessels. Even with a splenectomy and chemotherapy, dogs with HSA rarely live longer than 6 months. This paper describes the current treatment options for HSA, which are not very effective and do little to prolong your dog's life.
Dexter, who was born October 15th, 2009, was diagnosed with HSA and had a splenectomy in October, 2019. Dexter was given 3 months to live.
Dexter is alive because his owner did everything right - he had the HSA tumor removed with a splenectomy and started on GDF11 right away.
3+ years later and Dexter is cancer free, healthy and energetic. And he is the oldest living HSA dog on the planet.
The mechanism of action of HSA reversal is most likely GDF11's increasing endothelial repair as well as GDF11 targeting and reducing mitochondrial function of HSA tumor cells. Which either kills tumor cells or at least stops replication.
Also, once GDF11 clears your dog's HSA, if you keep your dog on a once per week GDF11 maintenance dose, HSA will NOT return. This is because GDF11 easily kills any new HSA tumors that may develop going forward.
You can read Dexter's HSA and GDF11 history from his Dog Dad here.
Read Dexter's entire veterinary history, from HSA diagnosis, to splenectomy to complete eradication of all HSA by GDF11.
Watch an energetic Dexter playing fetch years after beating HSA!
Fifty
Fifty is a 15 year old German Shepard who collapsed at the vet from HSA on May 3, 2020. Soon after he collapsed, Fifty had an emergency splenectomy.
After only a month on GDF11, Fifty returned to the vet for follow up exams. You can read all of the vet reports here.
Note that after only a month on GDF11, Fifty was cancer free and remains cancer free to this day.
Fifty is now back to his old self and has plenty of energy for a 15 year old dog.
We cannot emphasize enough how important it is to start on GDF11 right after your dog's HSA diagnosis. Hemangiosarcoma is like a California wildfire - it is very aggressive and spreads rapidly. GDF11 does very well at eradicating HSA if you start early.
Also, having the HSA tumor removed through splenectomy or other surgery gives GDF11 more of a fighting chance against any HSA that remains post surgery.
Click here to email Fifty's Dog Mom
Bella
Bella is a longhaired dachshund born November 5, 2008.
Bella had a splenectomy on September 3rd, 2020 and HSA was suspicioned. Liver biopsy was taken as well which came back benign. Spleen tumor came back malignant and confirmed HSA diagnosis.
Bella started on GDF11 on October 6, 2020. Her Dog Mom writes that Bella is back to chasing squirrels, something she hasn't done in years. She also has been scoring perfect 10's in her subjective biomarkers of energy, appetite gums and eyes.
Bella also now has very strong Emfit biomarkers often showing HRV of 150+, pulse of 55 and breaths per minute of 12.
Once again, Bella's owner moved quickly and decisively on GDF11 supplementation and that's why she's doing so well today.
View Bella's latest VDI tests:
Email Bella's Dog Mom Andi at Ramchop@Gmail.com
Fiona
Fiona
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Fiona is a
Pit Boxer/Rhodesian Ridgeback born on 1/1/2014.
After three days of lethargy Fiona was taken to VERG animal hospital in Brooklyn. At first she was (mis)diagnosed with a tick born illness, but after a night in the hospital with little recovery an ultrasound was done and a tumor on her spleen was found.
A splenectomy was recommended and performed on Friday evening 4/30/21. A baseball sized tumor was removed and was sent for biopsy, along with a liver sample.
During surgery the other organs showed no sign of tumors. A week later, 5/8/21, a biopsy result came back malignant, positive for hemangiosarcoma.
The liver biopsy showed negative results hinting that the cancer had not spread yet. Post-op Fiona's diet changed from kibble to Ollie's fresh dog food and she began FreshCap Turkey Tail.
Fiona commenced GDF11 injections on May 25th, 2021 and has been HSA free ever since then.
Roman
Fiona
Roman
Roman is a male Vizsla born May 5th, 2011
For the past 10.5 years, Roman has been an integral part of our life, one third of our family unit. We brought him home in July 2011, when he was 8 weeks old. Overall, he has led a very healthy, balanced, well-exercised, energized life.
He is always the fastest, liveliest dog at the park, even into his senior age. He is a bonafide speedbullet when we take him to Central Park off-leash after 9pm.
On August, 18, 2021, we rushed (carried) him to our vet where they ran blood work and performed a stomach scan. Blood work normal, scan showed liquid (blood) in his stomach. Very concerning.
They immediately predicted a mass on the spleen had ruptured and was internally hemorrhaging. A second ultrasound on his lungs did not reveal any further masses.
We rushed him to the ER. A third, more in-depth, abdominal ultra sound revealed that there were no further masses on his stomach organs other than the splenic one that had ruptured, so they determined he was a good candidate for an emergency splenectomy which they performed that night at around 7.30PM.
The surgery successfully removed the entire spleen with the mass and stopped the internal bleeding. We received biopsy results of mass on Roman's spleen: malignant for hemangiosarcoma (HSA).
Roman commenced GDF11 injections on September 7, 2021 and has fortunately been HSA free ever since then!
Myra
Fiona
Roman
Myra is a female decker terrier who was born May 10, 2011.
Myra was diagnosed with HSA on 6/14/21. Her Dog Dad Wally moved quickly to save Myra and she had a splenectomy on 7/6/21.
Myra commenced GDF11 injections on 7/18/21. Not only did GDF11 eradicate all HSA metastasis, but Myra started to see the rejuvenating effects of GDF11 such as improved coat, more energy and glistening eyes.
Mrya is still HSA free and is living the ultimate dog life in Koloa, Hawaii.
How to get your dog going on GDF11 injections with our extensive biomarker support
How to get your dog going on GDF11 injections with our extensive biomarker support
How to get your dog going on GDF11 injections with our extensive biomarker support
Interestingly enough, GDF11 has gone the opposite route of most peptides/drugs. It has been tested in humans for over 6 years and is fairly well understood. Only when a GDF11er gave some GDF11 to his dog Dexter (see above) did we learn that GDF11 can cure HSA!
Getting your dog going on GDF11 is a relatively simple process. Please start by printing, signing, scanning and emailing to us our standard release form.
Based on trending of your dog's heart rate variability, breaths per minute, pulse, etc., (which are measured nightly by an Emfit placed under his/her bed) we adjust the dose for optimal efficacy.
To cover our overhead, biomarker analysts and R&D expenses, we normally charge humans $15,000 for biomarker/dosing analysis.
Not surprisingly, HSA/lymphoma dogs often require much more biomarker analysis / dosing calls than humans do. But we love our dogs and cats and are willing to take a loss on our work to save our best friends. Therefore our fee for HSA dogs is only $3000.
We believe strongly in "pay for performance" and most of the fee, $2500, only needs to be paid once your dog reaches the 3 month mark on GDF11.
Only $500 of the fee needs to be paid up front. This is to cover our setup costs e.g., allometric analysis using your dog's age, weight and probable tumor load to determine optimal GDF11 starting dose. As well as creating a biomarker trending/dosing spreadsheet which you fill out when you dose your dog with GDF11.
We ask that you purchase the Emfit and GDF11 yourself. The Emfit is $250 and GDF11 is about $350.
If things do not work out, it is usually easy to resell Emfits/GDF11 on our Slack community since both are in short supply. We look forward to helping you with your HSA/lymphoma dog.
Learn more about GDF11
How to get your dog going on GDF11 injections with our extensive biomarker support
How to get your dog going on GDF11 injections with our extensive biomarker support
GDF11 is an endogenous (meaning it's natural and you have it in you) signaling molecule whose main mechanism of action is stem cell DNA repair.
Most of aging is likely caused by the atrophy of your stem cell populations due to declining GDF11 levels and many believe this is natural selection's way of programming lifespan.
GDF11 also has been shown to target cells with stem cell like qualities. All cancer cells exhibit "stemness" and GDF11 binds to tumor cells, disables mitochondrial function and kills them. Note that we have had success with dog lymphoma also as well as feline MCT. You can read more about this here.
Additionally, activating senescent stem cells, especially mesenchymal stem cells, results in increased endothelial repair and this is most likely another part of how GDF11 cures HSA.
Also, once GDF11 clears your dog's HSA, if you keep your dog on a once per week GDF11 maintenance dose, HSA will NOT return. This is because GDF11 easily kills any new HSA tumors that may develop going forward.
And here is a fascinating fact about GDF11 - it's molecular structure is conserved across all vertebrate species. Which means human, dog, cat and even orangutan GDF11 are identical.
This strongly suggests how important GDF11 is to life.
Click here to learn more about this fascinating molecule!