Hemangiosarcoma (HSA) is a rapidly growing, highly invasive cancer arising from the lining of blood vessels. Even with a splenectomy and chemotherapy, dogs with HSA rarely live longer than 6 months. This paper describes the current treatment options for HSA, which are not very effective and do little to prolong your dog's life.
Dexter, who is six years old, was diagnosed with HSA and had a splenectomy in October, 2019. Dexter was given 3 months to live. He started on chemo and GDF11 3x/week.
Dexter is alive because his owner did everything right - he had the HSA tumor removed and started on GDF11 right away.
12 Months later and Dexter is cancer free, healthy and energetic.
The mechanism of action of HSA reversal is most likely GDF11's increasing endothelial repair as well as GDF11 targeting and reducing mitochondrial function is HSA tumor cells. Which either kills tumor cells or at least stops replication.
You can read Dexter's HSA and GDF11 history here.
Fifty is a 14 year old German Shepard who collapsed at the vet from HSA on May 3, 2020. Soon after he collapsed, Fifty had an emergency splenectomy.
After only a month on GDF11, Fifty returned to the vet for follow up exams. You can read all of the vet reports here.
Note that after only a month on GDF11, Fifty was cancer free and remains cancer free to this day.
Fifty is now back to his old self and has plenty of energy for a 14 year old dog.
We cannot emphasize enough how important it is to start on GDF11 right after your dog's HSA diagnosis. Hemangiosarcoma is like a California wildfire - it is very aggressive and spreads rapidly. GDF11 does very well at eradicating HSA if you start early.
Also, having the HSA tumor removed through splenectomy or other surgery gives GDF11 more of a fighting chance against any HSA that remains post surgery.
Leo is a young German Shepard born on February, 13, 2013.
Leo was diagnosed with HSA and had his splenectomy on August 20th, 2020.
Fortunately, Leo's owner came to us quickly and started GDF11 on August, 29, 2020.
We are happy to report Leo is happy and energetic now. Here are a couple screenshots of his Emfits which show what an athlete Leo is!
Once again, Leo's owner moved quickly and decisively on GDF11 supplementation and that's why he's doing so well today.
Bella is a longhaired dachshund born November 5, 2008.
Bella had a splenectomy on September 3rd, 2020 and HSA was suspicioned. Liver biopsy was taken as well which came back benign. Spleen tumor came back malignant and confirmed HSA diagnosis.
Bella started on GDF11 on October 6, 2020. Her Dog Mom writes that Bella is back to chasing squirrels, something she hasn't done in years. She also has been scoring perfect 10's in her subjective biomarkers of energy, appetite gums and eyes.
Once again, Bella's owner moved quickly and decisively on GDF11 supplementation and that's why she's doing so well today.
Jake is a shepard/husky mix dog born on January 10, 2007
Jake's dog dad Ryan came to us right after Jake's HSA diagnosis. Ryan did not want to put Jake through a splenectomy. And fortunately the vet said his bleed was relatively mild.
So we got Jake going on megadoses of GDF11 right away and he's actually back to normal!
Of course, we have to be hyper vigilant and watch all of Jake's Emfit and other biomarkers for a possible HSA resurgence.
Here is a write up by Ryan on Jake's HSA history.
And here is a video of Jake frolicking on the beach just after one week on GDF11!
Interestingly enough, GDF11 has gone the opposite route of most peptides/drugs. It has been tested in humans for over 6 years and is fairly well understood. Only when a GDF11er gave some GDF11 to his dog Dexter (see above) did we learn that GDF11 can cure HSA!
Getting your dog going on GDF11 is a relatively simple process. Please start by printing, signing, scanning and emailing to us our standard release form.
We will then do an allometric analysis to determine your dog's optimal starting dose. We then send you a biomarker trending/dosing spreadsheet which you fill out when you dose your dog with GDF11.
Based on trending of your dog's heart rate variability and pulse, which is measured by an Emfit placed under his/her bed, we adjust the dose for optimal efficacy.
To cover our overhead and R&D expenses, we normally charge humans $15,000 for biomarker/dosing analysis.
We will be charging $3000 for HSA dogs starting January 1st, 2021, We are providing our services free of charge until then.
Since we are performing our services gratis, we ask that you purchase the Emfit and GDF11 yourself. The Emfit is $250 and GDF11 is about $300.
We look forward to helping you with your HSA dog.
GDF11 is an endogenous (meaning it's natural and you have it in you) signalling molecule whose main mechanism of action is stem cell DNA repair.
Most of aging is likely caused by the atrophy of your stem cell populations due to declining GDF11 levels and many believe this is natural selection's way of programming lifespan.
Activating senescent stem cells, especially mesenchymal stem cells, results in increased endothelial repair and this is most likely part of how GDF11 cures HSA.
Additionally, GDF11 has been shown to target cells with stem cell like qualities, which is another reason it is effective against HSA. You can read more about this here.
And here is a fascinating fact about GDF11 - it's molecular structure is conserved across all vertebrate species. Which means human, dog, cat and even orangutan GDF11 are identical.
This strongly suggests how important GDF11 is to life.
Click here to learn more about this fascinating molecule!
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